How Epigenetics Reduces Random Mutations
"We conclude that epigenetic mutational bias challenges the pevailing paradigm that mutation is a DIRECTIONLESS force in evolution. Our discovery yields a new account of the forces driving patterns of natural variation, CHALLENGING a LONG-STANDING PARADIGM regarding the randomness of mutation ." Nature 1/22 The intricate dance between genetics and environment shapes the phenotypic expression of an organism. While genetics provides the blueprint, epigenetics acts as a dynamic modulator, influencing how genes are expressed without altering the underlying DNA sequence. One crucial role of epigenetics is its contribution to maintaining genomic stability by mitigating the impact of random mutations . This essay delves into the mechanisms by which epigenetics modulates the reduction of random mutations, ensuring the fidelity of genetic information across generations. Understanding Random Mutations Random mutations are alterations in the DNA sequence ...